CD70

Across TCGA patient cohorts, CD70 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,884 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CD70-associated proteins across cancer lineages are PSMB10, WAS, and WIPF1. Each is linked with CD70 in more than 5 cancer types. Because this analysis shows association rather than direction, both CD70-to-partner and partner-to-CD70 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CD70 versus PSMB10 in BRCA, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CD70→partner) and Y-score (partner→CD70) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PSMB10 →	+0.444	+0.587	<.001	<.001	3	6
GBM	WAS →	+0.470	+0.953	<.001	<.001	3	6
BRCA	WIPF1 →	+0.578	+0.927	<.001	<.001	3	6
BRCA	NFKB2 →	+0.404	+0.918	<.001	<.001	3	6
UCEC	DEF6 →	+0.501	+0.589	<.001	<.001	3	6
BRCA	DOCK2 →	+0.500	+0.577	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,884 associations by consensus.

CD70 vs PSMB10 — BRCA

Explore this scatter interactively →