CD68

Across TCGA patient cohorts, CD68 protein abundance is significantly associated with the RNA expression of many other genes, with 3,518 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible CD68-associated genes across cancer lineages are RNA5SP61, CD33, and NCF2. Each is linked with CD68 in more than 2 cancer types. Because this analysis shows association rather than direction, both CD68-to-partner and partner-to-CD68 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CD68 versus RNA5SP61 in BRCA, with a Pearson correlation of -0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD68→partner) and Y-score (partner→CD68) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RNA5SP61 →	-1.288	-0.437	.001	.005	3	3
LUAD	CD33 →	+0.648	+0.371	<.001	.001	3	3
GBM	NCF2 →	+0.880	+0.736	.001	.004	3	3
OV	ALOX5AP →	+1.414	+0.409	.001	.009	3	3
GBM	DOK2 →	+0.938	+0.792	.003	.003	3	3
OV	FCER1G →	+1.277	+0.452	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,518 associations by consensus.

CD68 vs RNA5SP61 — BRCA

Explore this scatter interactively →