CD63

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CD63 mutation is significantly associated with the RNA expression of many other genes, with 112 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CD63-associated genes across cancer lineages are LINC02559, RN7SL248P, and RN7SKP181. Each is linked with CD63 in more than 1 cancer types. Because this analysis shows association rather than direction, both CD63-to-partner and partner-to-CD63 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02559 grouped by CD63-low versus CD63-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD63→partner) and Y-score (partner→CD63) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CESCLINC02559 →+1.780+6.342<.001.00132
CESCRN7SL248P →+0.212+7.584<.001<.00132
UCECRN7SKP181 →+0.173+3.133<.001.00932
UCECLINC01072 →+0.248+3.167<.001.00332
UCECUBL5P3 →+0.170+3.133.006.00932
UCECRN7SL354P →+0.307+2.695<.001.00732
Each partner links to its Q-omics profile. Showing the 6 strongest of 112 associations by consensus.

LINC02559 by CD63 expression — CESC

Box plot of LINC02559 in CD63-low vs CD63-high samples in CESC.

Explore this box plot interactively →

Exploration