CD6

Across TCGA patient cohorts, CD6 protein abundance is significantly associated with the RNA expression of many other genes, with 14,458 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CD6-associated genes across cancer lineages are GPR174, CD3G, and THEMIS. Each is linked with CD6 in more than 4 cancer types. Because this analysis shows association rather than direction, both CD6-to-partner and partner-to-CD6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CD6 versus GPR174 in CCRCC, with a Pearson correlation of 0.56.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD6→partner) and Y-score (partner→CD6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	GPR174 →	+1.509	+1.536	.006	.008	3	5
HNSC	CD3G →	+1.438	+1.026	.001	.002	3	5
CCRCC	THEMIS →	+1.171	+1.536	.001	.008	3	5
BRCA	CD3E →	+1.351	+0.796	<.001	<.001	3	5
CCRCC	TRAV13-1 →	+1.535	+1.625	.003	.004	3	5
HNSC	EOMES →	+1.025	+0.868	.002	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,458 associations by consensus.

CD6 vs GPR174 — CCRCC

Explore this scatter interactively →