CD5L

Across TCGA patient cohorts, CD5L protein abundance is significantly associated with the RNA expression of many other genes, with 13,001 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CD5L-associated genes across cancer lineages are CCL2, SEMA6B, and SERPINE1. Each is linked with CD5L in more than 5 cancer types. Because this analysis shows association rather than direction, both CD5L-to-partner and partner-to-CD5L results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CD5L versus CCL2 in GBM, with a Pearson correlation of 0.51.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD5L→partner) and Y-score (partner→CD5L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CCL2 →	+1.492	+0.591	<.001	<.001	3	6
COAD	SEMA6B →	+0.788	+0.762	<.001	<.001	3	6
LSCC	SERPINE1 →	+1.322	+0.662	<.001	<.001	3	5
OV	PCDH12 →	+0.730	+0.892	<.001	<.001	3	5
COAD	PLAUR →	+0.922	+0.714	<.001	<.001	3	5
OV	PDLIM2 →	+0.588	+0.769	.003	.009	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,001 associations by consensus.

CD5L vs CCL2 — GBM

Explore this scatter interactively →