CD5L

Across TCGA patient cohorts, CD5L mutation is significantly associated with the RNA expression of many other genes, with 1,194 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible CD5L-associated genes across cancer lineages are RNU6-922P, CENPN, and COX6B1P6. Each is linked with CD5L in more than 2 cancer types. Because this analysis shows association rather than direction, both CD5L-to-partner and partner-to-CD5L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-922P grouped by CD5L-low versus CD5L-high in PRAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD5L→partner) and Y-score (partner→CD5L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PRAD	RNU6-922P →	+0.496	+5.288	<.001	.006	3	3
LUAD	CENPN →	+0.806	+3.459	<.001	.005	3	3
PRAD	COX6B1P6 →	+0.303	+5.420	<.001	.005	3	3
BLCA	RNU6-792P →	+0.208	+4.859	<.001	.004	3	3
BLCA	RNU6-662P →	+0.290	+4.017	<.001	.004	3	3
BLCA	ATP6V1G1P5 →	+0.221	+4.320	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,194 associations by consensus.

RNU6-922P by CD5L expression — PRAD

Explore this box plot interactively →