CD5L

Across TCGA patient cohorts, CD5L mutation is significantly associated with the total protein of many other genes, with 34 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CD5L-associated genes across cancer lineages are Acetyl-a-Tubulin-Lys40, ATM, and PDK1. Each is linked with CD5L in more than 4 cancer types. Because this analysis shows association rather than direction, both CD5L-to-partner and partner-to-CD5L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Acetyl-a-Tubulin-Lys40 grouped by CD5L-low versus CD5L-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD5L→partner) and Y-score (partner→CD5L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	Acetyl-a-Tubulin-Lys40 →	+0.437	+1.678	.037	.022	3	5
LUSC	ATM →	-0.610	-3.321	.003	.009	3	3
LUSC	PDK1 →	+0.173	+1.883	<.001	.031	3	2
LUSC	Rad50 →	-0.182	-3.000	.001	.033	3	2
LUSC	S6 →	+0.263	+3.000	.027	.035	3	2
LUAD	MEK1_p_S217_S221 →	-0.234	-3.169	.028	.019	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 34 associations by consensus.

Acetyl-a-Tubulin-Lys40 by CD5L expression — SKCM

Explore this box plot interactively →