CD5L

Across TCGA cell cohorts, CD5L RNA expression is significantly associated with the go_rna of many other GO terms, with 638 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible CD5L-associated GO terms across cancer lineages are T-helper 17 cell differentiation, Regulation of protein localization to chromosome, telomeric region, and Circadian rhythm. Each is linked with CD5L in more than 5 cancer types. Because this analysis shows association rather than direction, both CD5L-to-partner and partner-to-CD5L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, T-helper 17 cell differentiation grouped by CD5L-low versus CD5L-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CD5L→partner) and Y-score (partner→CD5L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	T-helper 17 cell differentiation →	+0.085	+0.022	.003	.008	2	6
LIVER	Regulation of protein localization to chromosome, telomeric region →	+0.071	+0.022	.005	.001	2	6
LUNG_NSCLC_LUAD	Circadian rhythm →	+0.071	+0.030	<.001	.005	3	4
LIVER	T-helper 17 type immune response →	+0.104	+0.022	.005	.009	3	4
UPPER_AERODIGESTIVE_TRACT	Regulation of vasculature development →	+0.056	+0.016	<.001	.005	3	4
UPPER_AERODIGESTIVE_TRACT	Regulation of cytokine-mediated signaling pathway →	+0.069	+0.029	.002	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 638 associations by consensus.

T-helper 17 cell differentiation by CD5L expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →