CD5L

Across TCGA cell cohorts, CD5L mutation is significantly associated with the drug of many other genes, with 16 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CD5L-associated genes across cancer lineages are Alisertib, 741909, and SU11274. Each is linked with CD5L in more than 1 cancer types. Because this analysis shows association rather than direction, both CD5L-to-partner and partner-to-CD5L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Alisertib grouped by CD5L-low versus CD5L-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD5L→partner) and Y-score (partner→CD5L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Alisertib →	+0.729	+2.646	.045	.047	3	1
LARGE_INTESTINE	741909 →	+0.567	+2.649	.033	.046	2	2
LARGE_INTESTINE	SU11274 →	+0.630	+2.652	.001	.045	3	1
LARGE_INTESTINE	PRT062607 →	+0.536	+2.769	.034	.040	2	1
LARGE_INTESTINE	GSK2110183B →	+0.652	+2.649	.032	.046	2	1
LARGE_INTESTINE	Sinularin →	+0.390	+2.777	.012	.038	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

Alisertib by CD5L expression — LARGE_INTESTINE

Explore this box plot interactively →