Across TCGA patient cohorts, CD55 protein abundance is significantly associated with the RNA expression of many other genes, with 8,454 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CD55-associated genes across cancer lineages are ACTA2, FN1, and PLA2G5. Each is linked with CD55 in more than 5 cancer types. Because this analysis shows association rather than direction, both CD55-to-partner and partner-to-CD55 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD55→partner) and Y-score (partner→CD55) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ACTA2 →	+1.742	+0.938	<.001	<.001	3	6
OV	FN1 →	+1.488	+0.749	<.001	<.001	3	6
COAD	PLA2G5 →	+0.473	+0.479	.002	.002	3	6
BRCA	LOXL1 →	+1.108	+0.699	<.001	<.001	3	6
OV	PRICKLE1 →	+0.775	+0.779	<.001	<.001	3	6
BRCA	RCN3 →	+1.028	+0.747	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,454 associations by consensus.

Exploration

CD55 survival (RNA) · tumor vs normal (RNA) · all CD55 data types