Across TCGA patient cohorts, CD55 mutation is significantly associated with the RNA expression of many other genes, with 1,754 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CD55-associated genes across cancer lineages are MIR4535, BTBD10, and SSRP1. Each is linked with CD55 in more than 1 cancer types. Because this analysis shows association rather than direction, both CD55-to-partner and partner-to-CD55 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD55→partner) and Y-score (partner→CD55) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MIR4535 →	+0.361	+4.993	<.001	.002	3	2
UCEC	BTBD10 →	+0.472	+3.823	.002	<.001	3	1
UCEC	SSRP1 →	+0.471	+2.513	.007	.009	3	1
UCEC	LAMTOR1 →	+0.321	+3.617	.007	.001	3	1
UCEC	MTA2 →	+0.398	+2.471	.002	.001	3	1
UCEC	FADS1 →	+0.907	+3.321	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,754 associations by consensus.

Exploration

CD55 survival (RNA) · tumor vs normal (RNA) · all CD55 data types