Across TCGA patient cohorts, CD55 mutation is significantly associated with the total protein of many other genes, with 23 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CD55-associated genes across cancer lineages are mTOR_pS2448, Caspase-7-cleavedD198, and EGFR_pY1068. Each is linked with CD55 in more than 1 cancer types. Because this analysis shows association rather than direction, both CD55-to-partner and partner-to-CD55 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD55→partner) and Y-score (partner→CD55) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	mTOR_pS2448 →	-0.146	-2.308	.017	.033	3	2
UCEC	Caspase-7-cleavedD198 →	+0.496	+3.479	.042	.002	3	2
UCEC	EGFR_pY1068 →	-0.268	-1.807	.009	.027	3	1
UCEC	FASN →	+0.407	+2.321	.012	.006	3	1
UCEC	JNK_pT183_Y185 →	-0.202	-3.459	.003	.005	3	1
UCEC	JNK2 →	+0.254	+3.469	.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

Exploration

CD55 survival (RNA) · tumor vs normal (RNA) · all CD55 data types