CD5

Across TCGA cell cohorts, CD5 mutation is significantly associated with the RNA expression of many other genes, with 27 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CD5-associated genes across cancer lineages are OR7G1, OR10A4, and FAM187B. Each is linked with CD5 in more than 1 cancer types. Because this analysis shows association rather than direction, both CD5-to-partner and partner-to-CD5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR7G1 grouped by CD5-low versus CD5-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD5→partner) and Y-score (partner→CD5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	OR7G1 →	+0.017	+5.266	<.001	.001	3	1
LARGE_INTESTINE	OR10A4 →	+0.061	+3.453	<.001	.009	3	1
LARGE_INTESTINE	FAM187B →	+0.027	+3.347	<.001	.005	3	1
LARGE_INTESTINE	FCAR →	+0.024	+3.345	<.001	.007	3	1
STOMACH	TRIM49D2 →	+0.040	+5.285	<.001	.003	3	1
BLOOD_Leukemia	SLC32A1 →	+0.990	+3.901	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 27 associations by consensus.

OR7G1 by CD5 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →