CD48

Across TCGA patient cohorts, CD48 mutation is significantly associated with the RNA expression of many other genes, with 2,392 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CD48-associated genes across cancer lineages are MIR6816, GPATCH11, and CWC27. Each is linked with CD48 in more than 2 cancer types. Because this analysis shows association rather than direction, both CD48-to-partner and partner-to-CD48 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6816 grouped by CD48-low versus CD48-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD48→partner) and Y-score (partner→CD48) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	MIR6816 →	+0.532	+4.888	<.001	.005	3	3
UCEC	GPATCH11 →	+0.481	+3.010	.001	<.001	3	2
UCEC	CWC27 →	+0.528	+3.524	.003	.002	3	2
UCEC	GBP5 →	+1.092	+3.010	.001	<.001	3	2
UCEC	SASS6 →	+0.568	+2.321	.005	.006	3	2
UCEC	GPATCH4 →	+0.557	+2.343	.005	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,392 associations by consensus.

MIR6816 by CD48 expression — LUAD

Explore this box plot interactively →