CD48

Across TCGA cell cohorts, CD48 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,444 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CD48-associated GO terms across cancer lineages are Regulation of translational initiation, ATP metabolic process, and Regulation of syncytium formation by plasma membrane fusion. Each is linked with CD48 in more than 8 cancer types. Because this analysis shows association rather than direction, both CD48-to-partner and partner-to-CD48 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of translational initiation grouped by CD48-low versus CD48-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CD48→partner) and Y-score (partner→CD48) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Regulation of translational initiation →	+0.070	+0.159	<.001	.004	3	7
OESOPHAGUS	ATP metabolic process →	+0.124	+0.193	.004	.007	1	9
OESOPHAGUS	Regulation of syncytium formation by plasma membrane fusion →	+0.138	+0.193	.002	.009	3	6
STOMACH	Positive regulation of respiratory burst →	-0.218	-0.145	<.001	.001	2	7
LARGE_INTESTINE	Mitochondrial electron transport, cytochrome c to oxygen →	+0.048	+0.169	<.001	.001	3	6
LARGE_INTESTINE	Striated muscle contraction →	+0.036	+0.186	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,444 associations by consensus.

Regulation of translational initiation by CD48 expression — LARGE_INTESTINE

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