CD48

Across TCGA cell cohorts, CD48 mutation is significantly associated with the mutation status of many other genes, with 2,896 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CD48-associated genes across cancer lineages are MEOX1, TUBE1, and IRF6. Each is linked with CD48 in more than 1 cancer types. Because this analysis shows association rather than direction, both CD48-to-partner and partner-to-CD48 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MEOX1 grouped by CD48-low versus CD48-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD48→partner) and Y-score (partner→CD48) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	MEOX1 →	+3.584	+3.007	.008	.008	1	2
LARGE_INTESTINE	TUBE1 →	+4.000	+3.459	<.001	<.001	1	2
LARGE_INTESTINE	IRF6 →	+3.415	+3.215	.002	.002	1	2
LARGE_INTESTINE	CFAP94 →	+3.000	+3.000	.003	.003	1	2
LARGE_INTESTINE	H1-3 →	+3.415	+3.215	.002	.002	1	2
LARGE_INTESTINE	FAM110A →	+3.415	+3.215	.002	.002	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,896 associations by consensus.

MEOX1 by CD48 expression — LARGE_INTESTINE

Explore this box plot interactively →