CD48

Across TCGA cell cohorts, CD48 mutation is significantly associated with the drug of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CD48-associated genes across cancer lineages are Afatinib and WZ4003. Each is linked with CD48 in more than 1 cancer types. Because this analysis shows association rather than direction, both CD48-to-partner and partner-to-CD48 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Afatinib grouped by CD48-low versus CD48-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD48→partner) and Y-score (partner→CD48) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Afatinib →	+0.606	+2.646	.035	.047	1	1
LARGE_INTESTINE	WZ4003 →	+0.427	+2.769	.040	.040	1	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Afatinib by CD48 expression — LARGE_INTESTINE

Explore this box plot interactively →