Across TCGA patient cohorts, CD47 protein abundance is significantly associated with the RNA expression of many other genes, with 17,816 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CD47-associated genes across cancer lineages are VNN3, COCH, and TBL1X. Each is linked with CD47 in more than 4 cancer types. Because this analysis shows association rather than direction, both CD47-to-partner and partner-to-CD47 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD47→partner) and Y-score (partner→CD47) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	VNN3 →	+1.073	+0.548	<.001	<.001	3	5
HNSC	COCH →	-1.232	-0.465	<.001	<.001	3	4
LSCC	TBL1X →	-0.955	-0.505	<.001	<.001	3	4
HNSC	H2AZ2 →	-0.688	-0.389	.004	.004	3	4
LSCC	GIT1 →	-0.953	-0.586	<.001	<.001	3	4
LUAD	IL12B →	+0.655	+0.427	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,816 associations by consensus.

Exploration

CD47 survival (RNA) · tumor vs normal (RNA) · all CD47 data types