Across TCGA patient cohorts, CD47 mutation is significantly associated with the total protein of many other genes, with 9 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CD47-associated genes across cancer lineages are C-Raf, JNK2, and Ku80. Each is linked with CD47 in more than 1 cancer types. Because this analysis shows association rather than direction, both CD47-to-partner and partner-to-CD47 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD47→partner) and Y-score (partner→CD47) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	C-Raf →	+0.179	+2.321	.003	.033	3	2
UCEC	JNK2 →	+0.241	+3.026	.004	.018	3	1
UCEC	Ku80 →	+0.271	+1.713	.006	.027	3	1
UCEC	MEK1 →	+0.450	+3.459	.003	.005	3	1
UCEC	PDK1_pS241 →	+0.196	+1.713	.006	.027	3	1
UCEC	Tuberin →	+0.305	+1.700	.007	.044	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

Exploration

CD47 survival (RNA) · tumor vs normal (RNA) · all CD47 data types