CD44

Across TCGA patient cohorts, CD44 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,325 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CD44-associated proteins across cancer lineages are CD44_S706, MYO1G, and ALOX5. Each is linked with CD44 in more than 5 cancer types. Because this analysis shows association rather than direction, both CD44-to-partner and partner-to-CD44 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CD44 versus CD44_S706 in LSCC, with a Pearson correlation of 0.46.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CD44→partner) and Y-score (partner→CD44) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CD44_S706 →	+1.145	+1.097	<.001	<.001	3	6
GBM	MYO1G →	+0.523	+1.006	<.001	<.001	3	5
GBM	ALOX5 →	+0.570	+0.821	<.001	<.001	3	5
BRCA	WAC →	-0.193	-0.735	.001	.001	3	5
GBM	CRYBG1 →	+0.550	+1.212	<.001	<.001	3	5
CCRCC	FCGBP →	+1.010	+1.024	.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,325 associations by consensus.

CD44 vs CD44_S706 — LSCC

Explore this scatter interactively →