CD3G

Across TCGA patient cohorts, CD3G mutation is significantly associated with the RNA expression of many other genes, with 484 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CD3G-associated genes across cancer lineages are BMS1P14, RNA5SP456, and IGHVII-44-2. Each is linked with CD3G in more than 1 cancer types. Because this analysis shows association rather than direction, both CD3G-to-partner and partner-to-CD3G results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BMS1P14 grouped by CD3G-low versus CD3G-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD3G→partner) and Y-score (partner→CD3G) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	BMS1P14 →	+0.488	+4.163	<.001	.003	3	2
LUSC	RNA5SP456 →	+0.412	+4.297	<.001	.009	3	2
LUSC	IGHVII-44-2 →	+0.564	+3.849	<.001	.006	3	2
COAD	RPS29P1 →	+0.249	+7.741	.001	.009	3	1
BLCA	LINC00904 →	+0.138	+5.788	<.001	.003	3	1
UCEC	IGLV2-8 →	+2.272	+3.459	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 484 associations by consensus.

BMS1P14 by CD3G expression — SKCM

Explore this box plot interactively →