CD3G

Across TCGA cell cohorts, CD3G RNA expression is significantly associated with the go_rna of many other GO terms, with 2,176 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CD3G-associated GO terms across cancer lineages are Phospholipid biosynthetic process, Golgi vesicle transport, and Regulation of translational initiation. Each is linked with CD3G in more than 5 cancer types. Because this analysis shows association rather than direction, both CD3G-to-partner and partner-to-CD3G results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Phospholipid biosynthetic process grouped by CD3G-low versus CD3G-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CD3G→partner) and Y-score (partner→CD3G) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Phospholipid biosynthetic process →	+0.026	+0.057	<.001	<.001	3	6
LARGE_INTESTINE	Golgi vesicle transport →	+0.034	+0.060	.003	.004	3	5
OESOPHAGUS	Regulation of translational initiation →	+0.082	+0.077	.005	.009	3	5
LUNG_NSCLC_LUSC	Oxidative demethylation →	-0.146	-0.032	<.001	.004	3	5
LARGE_INTESTINE	Positive regulation of cytoplasmic translation →	+0.065	+0.064	.004	.003	3	5
OESOPHAGUS	Spindle assembly →	+0.059	+0.050	.009	.004	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,176 associations by consensus.

Phospholipid biosynthetic process by CD3G expression — LARGE_INTESTINE

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