CD3D

Across TCGA patient cohorts, CD3D protein abundance is significantly associated with the RNA expression of many other genes, with 11,479 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CD3D-associated genes across cancer lineages are GZMK, LY9, and ZNF831. Each is linked with CD3D in more than 4 cancer types. Because this analysis shows association rather than direction, both CD3D-to-partner and partner-to-CD3D results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CD3D versus GZMK in BRCA, with a Pearson correlation of 0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD3D→partner) and Y-score (partner→CD3D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	GZMK →	+1.504	+1.029	.001	<.001	3	5
LSCC	LY9 →	+0.984	+0.563	<.001	<.001	3	5
UCEC	ZNF831 →	+1.431	+0.656	<.001	.008	3	5
LSCC	PRKCB →	+1.056	+0.617	<.001	<.001	3	5
HNSC	SHISAL2A →	+0.823	+0.764	.001	<.001	3	5
CCRCC	CLECL1 →	+1.109	+0.602	.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,479 associations by consensus.

CD3D vs GZMK — BRCA

Explore this scatter interactively →