CD3D

Across TCGA cell cohorts, CD3D RNA expression is significantly associated with the go_rna of many other GO terms, with 2,336 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CD3D-associated GO terms across cancer lineages are Regulation of telomere maintenance via telomere lengthening, Positive thymic T cell selection, and Regulated exocytosis. Each is linked with CD3D in more than 7 cancer types. Because this analysis shows association rather than direction, both CD3D-to-partner and partner-to-CD3D results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of telomere maintenance via telomere lengthening grouped by CD3D-low versus CD3D-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CD3D→partner) and Y-score (partner→CD3D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Regulation of telomere maintenance via telomere lengthening →	+0.065	+0.352	.001	.003	3	7
LUNG_NSCLC_LUAD	Positive thymic T cell selection →	-0.892	-0.174	<.001	<.001	2	8
BLOOD_Leukemia	Regulated exocytosis →	-0.055	-4.533	<.001	<.001	3	7
CNS	Regulation of syncytium formation by plasma membrane fusion →	+0.049	+0.217	<.001	.002	2	8
PANCREAS	Viral gene expression →	+0.103	+0.489	<.001	.009	2	7
CNS	Negative regulation of myoblast fusion →	+0.062	+0.316	<.001	<.001	2	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,336 associations by consensus.

Regulation of telomere maintenance via telomere lengthening by CD3D expression — URINARY_TRACT

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