CD36

Across TCGA patient cohorts, CD36 mutation is significantly associated with the total protein of many other genes, with 37 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CD36-associated genes across cancer lineages are EGFR, mTOR_pS2448, and p38-MAPK_pT180_Y182. Each is linked with CD36 in more than 1 cancer types. Because this analysis shows association rather than direction, both CD36-to-partner and partner-to-CD36 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EGFR grouped by CD36-low versus CD36-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD36→partner) and Y-score (partner→CD36) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EGFR →	-0.191	-1.973	.001	.029	3	2
UCEC	mTOR_pS2448 →	-0.138	-1.980	.015	.030	3	2
UCEC	p38-MAPK_pT180_Y182 →	-0.423	-2.115	.014	.017	3	2
UCEC	ATM →	-0.655	-2.584	<.001	.010	3	2
SKCM	SCD →	+0.214	+3.321	.004	.010	3	2
UCEC	14-3-3_beta →	-0.087	-1.847	.023	.049	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 37 associations by consensus.

EGFR by CD36 expression — UCEC

Explore this box plot interactively →