CD36

Across TCGA pan-cancer cohorts, CD36 RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of CD36’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where CD36 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CD36 is over-expressed in tumor, although a few such as COAD and LUAD show the opposite, repressed pattern.

KIRC, COAD, and LUAD are the cancer types where CD36 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CD36 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	All	+2.484	<.001	12	view →
COAD	Female	III,IV	−2.461	<.001	12	view →
LUAD	Female	III,IV	−3.748	<.001	11	view →
THCA	All	IV	−3.060	<.001	11	view →
LUSC	All	II,III,IV	−2.871	<.001	9	view →
BRCA	All	All	−3.844	<.001	6	view →
UCEC	All	III,IV	−2.156	<.001	6	view →
STAD	All	All	−1.213	<.001	5	view →
LIHC	All	II,III,IV	+1.178	.003	5	view →
READ	Female	All	−2.563	<.001	3	view →
KICH	All	All	−1.090	<.001	3	view →
CHOL	Female	All	−1.700	.017	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

CD36–KIRC

Open the KIRC breakdown →