CD300LG

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CD300LG mutation is significantly associated with the RNA expression of many other genes, with 1,471 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CD300LG-associated genes across cancer lineages are PECR, RNA5SP417, and TUBB1P2. Each is linked with CD300LG in more than 2 cancer types. Because this analysis shows association rather than direction, both CD300LG-to-partner and partner-to-CD300LG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PECR grouped by CD300LG-low versus CD300LG-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD300LG→partner) and Y-score (partner→CD300LG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMPECR →+0.670+3.706.009<.00133
UCECRNA5SP417 →+0.506+1.936<.001.00933
LUSCTUBB1P2 →+0.020+4.438<.001<.00133
UCECZMYND19 →+0.404+1.797.001.00833
LUADRNU6-451P →+0.310+3.205.004.00232
UCECINO80B-WBP1 →+0.072+1.883.006.00732
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,471 associations by consensus.

PECR by CD300LG expression — SKCM

Box plot of PECR in CD300LG-low vs CD300LG-high samples in SKCM.

Explore this box plot interactively →

Exploration