Across TCGA patient cohorts, CD300LD mutation is significantly associated with the total protein of many other genes, with 34 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CD300LD-associated genes across cancer lineages are STAT3_pY705, p38-MAPK_pT180_Y182, and PDCD4. Each is linked with CD300LD in more than 2 cancer types. Because this analysis shows association rather than direction, both CD300LD-to-partner and partner-to-CD300LD results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD300LD→partner) and Y-score (partner→CD300LD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	STAT3_pY705 →	-0.405	-1.906	<.001	.016	3	3
UCEC	p38-MAPK_pT180_Y182 →	-0.450	-1.893	.012	.016	3	2
UCEC	PDCD4 →	-0.800	-2.690	<.001	.006	2	3
UCEC	PKC-b-II_pS660 →	-0.254	-1.906	.022	.016	3	2
COAD	ASNS →	+0.919	+2.815	<.001	.036	3	2
UCEC	ATM →	-0.563	-2.571	.001	.010	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 34 associations by consensus.

Exploration

CD300LD survival (RNA) · tumor vs normal (RNA) · all CD300LD data types