Across TCGA pan-cancer cohorts, CD300LD RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of CD300LD’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where CD300LD RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CD300LD is over-expressed in tumor, although a few such as LUSC and KICH show the opposite, repressed pattern.

COAD, LUSC, and KICH are the cancer types where CD300LD tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CD300LD RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	All	+0.198	<.001	6	view →
LUSC	Male	All	−0.084	.001	2	view →
KICH	All	All	−0.034	.009	2	view →
KIRC	Male	All	+0.020	.019	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: CD300LD RNA expression & survival · all CD300LD data types