CD300A

Across TCGA patient cohorts, CD300A mutation is significantly associated with the total protein of many other genes, with 26 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CD300A-associated genes across cancer lineages are p62 Lck ligand, Di-Ras3, and FoxM1. Each is linked with CD300A in more than 1 cancer types. Because this analysis shows association rather than direction, both CD300A-to-partner and partner-to-CD300A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, p62 Lck ligand grouped by CD300A-low versus CD300A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD300A→partner) and Y-score (partner→CD300A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	p62 Lck ligand →	+0.372	+3.009	.018	.019	3	2
UCEC	Di-Ras3 →	-0.220	-2.986	.002	.035	3	2
UCEC	FoxM1 →	+0.329	+2.459	.008	.020	3	1
UCEC	ACC_pS79 →	+0.407	+2.817	.015	.036	3	1
UCEC	HSP70 →	-0.440	-3.160	.023	.019	3	1
UCEC	INPP4B →	-0.355	-2.999	.023	.035	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 26 associations by consensus.

p62 Lck ligand by CD300A expression — UCEC

Explore this box plot interactively →