CD2BP2

Across TCGA patient cohorts, CD2BP2 mutation is significantly associated with the RNA expression of many other genes, with 605 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CD2BP2-associated genes across cancer lineages are MIR4504, RNU6-921P, and ATP5F1EP1. Each is linked with CD2BP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CD2BP2-to-partner and partner-to-CD2BP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR4504 grouped by CD2BP2-low versus CD2BP2-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD2BP2→partner) and Y-score (partner→CD2BP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	MIR4504 →	+0.484	+5.320	<.001	.001	3	2
COAD	RNU6-921P →	+0.541	+4.516	<.001	.009	3	2
UCEC	ATP5F1EP1 →	+0.220	+2.255	.008	.009	3	2
SKCM	SNORD111B →	+0.381	+3.979	<.001	.003	3	2
BLCA	RNU6-456P →	+0.330	+6.307	<.001	<.001	3	2
UCEC	TIMM8B →	+0.430	+3.212	.009	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 605 associations by consensus.

MIR4504 by CD2BP2 expression — BLCA

Explore this box plot interactively →