CD244

Across TCGA patient cohorts, CD244 mutation is significantly associated with the RNA expression of many other genes, with 1,041 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CD244-associated genes across cancer lineages are HNRNPA3P16, ELF2P3, and RNU6-39P. Each is linked with CD244 in more than 1 cancer types. Because this analysis shows association rather than direction, both CD244-to-partner and partner-to-CD244 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HNRNPA3P16 grouped by CD244-low versus CD244-high in READ.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD244→partner) and Y-score (partner→CD244) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	HNRNPA3P16 →	+0.137	+5.219	<.001	.006	3	2
BLCA	ELF2P3 →	+0.035	+4.973	.004	.009	3	2
UCEC	RNU6-39P →	+0.281	+2.077	.007	.007	3	2
SKCM	RN7SKP172 →	+0.071	+2.596	.001	.008	3	2
LUAD	OR4K17 →	+0.050	+5.523	<.001	.001	3	2
LUAD	SELENOTP2 →	+0.106	+3.926	.002	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,041 associations by consensus.

HNRNPA3P16 by CD244 expression — READ

Explore this box plot interactively →