CD22

Across TCGA patient cohorts, CD22 protein abundance is significantly associated with the RNA expression of many other genes, with 9,703 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible CD22-associated genes across cancer lineages are PRKCB, LINC00494, and COL6A6. Each is linked with CD22 in more than 2 cancer types. Because this analysis shows association rather than direction, both CD22-to-partner and partner-to-CD22 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CD22 versus PRKCB in LUAD, with a Pearson correlation of 0.73.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD22→partner) and Y-score (partner→CD22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	PRKCB →	+1.078	+1.173	<.001	.006	3	3
PDAC	LINC00494 →	+1.112	+0.945	.001	<.001	3	3
LSCC	COL6A6 →	+1.201	+0.943	<.001	<.001	3	2
HNSC	TMEM167AP1 →	+1.172	+1.475	.002	.009	3	2
LSCC	LINC02422 →	+0.615	+0.572	<.001	<.001	3	2
PDAC	SNW1 →	-0.487	-0.855	.002	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,703 associations by consensus.

CD22 vs PRKCB — LUAD

Explore this scatter interactively →