CD200

Across TCGA patient cohorts, CD200 mutation is significantly associated with the total protein of many other genes, with 12 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CD200-associated genes across cancer lineages are ASNS, JNK_pT183_Y185, and MEK1. Each is linked with CD200 in more than 1 cancer types. Because this analysis shows association rather than direction, both CD200-to-partner and partner-to-CD200 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASNS grouped by CD200-low versus CD200-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD200→partner) and Y-score (partner→CD200) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ASNS →	+0.590	+3.000	.002	.036	3	2
UCEC	JNK_pT183_Y185 →	-0.224	-3.156	.015	.020	3	1
UCEC	MEK1 →	+0.507	+3.169	.011	.019	3	1
UCEC	Myosin-IIa_pS1943 →	+0.230	+3.183	.042	.010	3	1
UCEC	PRAS40_pT246 →	+0.225	+3.183	.017	.010	3	1
UCEC	Rictor_pT1135 →	-0.125	-3.169	.026	.020	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

ASNS by CD200 expression — UCEC

Explore this box plot interactively →