CD1A

Across TCGA patient cohorts, CD1A mutation is significantly associated with the RNA expression of many other genes, with 3,430 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CD1A-associated genes across cancer lineages are NCAPH2, RBMY3AP, and SEBOX. Each is linked with CD1A in more than 2 cancer types. Because this analysis shows association rather than direction, both CD1A-to-partner and partner-to-CD1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NCAPH2 grouped by CD1A-low versus CD1A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD1A→partner) and Y-score (partner→CD1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NCAPH2 →	+0.692	+3.523	<.001	<.001	3	3
LUAD	RBMY3AP →	+0.035	+3.912	<.001	.009	3	3
HNSC	SEBOX →	+0.069	+4.624	.005	.004	3	3
UCEC	RNU4-58P →	+0.156	+2.133	.003	.007	3	3
BLCA	SNORD90 →	+0.298	+3.971	.002	.005	3	3
UCEC	RNA5SP496 →	+0.400	+1.928	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,430 associations by consensus.

NCAPH2 by CD1A expression — UCEC

Explore this box plot interactively →