Across TCGA patient cohorts, CD177 mutation is significantly associated with the RNA expression of many other genes, with 983 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CD177-associated genes across cancer lineages are RNU4-31P, RNU6-577P, and RNU6-1315P. Each is linked with CD177 in more than 1 cancer types. Because this analysis shows association rather than direction, both CD177-to-partner and partner-to-CD177 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD177→partner) and Y-score (partner→CD177) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	RNU4-31P →	+0.289	+3.608	.005	.002	3	2
SKCM	RNU6-577P →	+0.312	+2.059	<.001	.008	3	2
SKCM	RNU6-1315P →	+0.212	+2.177	.005	.003	3	2
BLCA	S100A7L2 →	+0.117	+5.329	.002	.006	3	2
LUAD	PSAT1P4 →	+0.177	+4.157	<.001	.003	3	2
UCEC	AP1B1 →	+0.514	+2.191	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 983 associations by consensus.

Exploration

CD177 survival (RNA) · tumor vs normal (RNA) · all CD177 data types