CD163L1

Across TCGA patient cohorts, CD163L1 mutation is significantly associated with the RNA expression of many other genes, with 4,620 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CD163L1-associated genes across cancer lineages are ZWINT, H2AZ1, and CDCA2. Each is linked with CD163L1 in more than 4 cancer types. Because this analysis shows association rather than direction, both CD163L1-to-partner and partner-to-CD163L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZWINT grouped by CD163L1-low versus CD163L1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD163L1→partner) and Y-score (partner→CD163L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ZWINT →	+0.491	+1.718	<.001	<.001	3	5
LUAD	H2AZ1 →	+0.517	+3.169	.001	<.001	3	5
COAD	CDCA2 →	+0.666	+3.342	.006	.005	3	5
STAD	PBK →	+0.851	+3.717	.006	<.001	3	5
UCEC	RRM2 →	+0.548	+1.621	.001	<.001	3	5
UCEC	NUP188 →	+0.413	+1.980	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,620 associations by consensus.

ZWINT by CD163L1 expression — UCEC

Explore this box plot interactively →