CD151

Across TCGA patient cohorts, CD151 mutation is significantly associated with the total protein of many other genes, with 19 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CD151-associated genes across cancer lineages are FoxM1, FOXO3a_pS318_S321, and INPP4B. Each is linked with CD151 in more than 1 cancer types. Because this analysis shows association rather than direction, both CD151-to-partner and partner-to-CD151 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FoxM1 grouped by CD151-low versus CD151-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD151→partner) and Y-score (partner→CD151) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FoxM1 →	+0.364	+3.169	.010	.020	3	1
UCEC	FOXO3a_pS318_S321 →	-0.207	-2.990	.002	.036	3	1
UCEC	INPP4B →	-0.392	-3.156	.027	.020	3	1
UCEC	p62 Lck ligand →	+0.503	+2.817	.004	.036	3	1
UCEC	PCNA →	+0.354	+3.000	.002	.036	3	1
UCEC	Stathmin →	+0.181	+3.169	.016	.020	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

FoxM1 by CD151 expression — UCEC

Explore this box plot interactively →