CD151

Across TCGA pan-cancer cohorts, CD151 RNA differs between tumor and matched normal tissue in 15 of 18 cancer types tested, making tumor–normal expression one of CD151’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where CD151 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CD151 is over-expressed in tumor, although a few such as LUSC and KICH show the opposite, repressed pattern.

KIRC, HNSC, and KIRP are the cancer types where CD151 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CD151 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	All	+1.113	<.001	12	view →
HNSC	Female	All	+1.234	<.001	11	view →
KIRP	All	II,III,IV	+1.111	<.001	11	view →
THCA	Male	All	+1.041	<.001	10	view →
LIHC	Female	II,III,IV	+1.951	<.001	9	view →
LUSC	Female	All	−1.072	<.001	7	view →
KICH	All	All	−0.852	<.001	5	view →
STAD	Male	II,III,IV	+0.829	.003	4	view →
BRCA	All	II,III,IV	−0.439	<.001	4	view →
CHOL	All	All	+2.585	<.001	3	view →
LUAD	All	All	−0.399	.001	3	view →
ESCA	All	All	+1.056	.004	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 15 lineages.

CD151–KIRC

Open the KIRC breakdown →