CCZ1

Across TCGA patient cohorts, CCZ1 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,943 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible CCZ1-associated proteins across cancer lineages are POLR1E, HDDC3, and KBTBD2. Each is linked with CCZ1 in more than 4 cancer types. Because this analysis shows association rather than direction, both CCZ1-to-partner and partner-to-CCZ1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCZ1 versus POLR1E in BRCA, with a Pearson correlation of 0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CCZ1→partner) and Y-score (partner→CCZ1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	POLR1E →	+0.337	+0.626	.001	<.001	3	5
BRCA	HDDC3 →	-0.460	-0.628	<.001	<.001	3	4
PDAC	KBTBD2 →	+0.318	+0.455	<.001	<.001	3	4
BRCA	ANLN →	+0.732	+0.667	<.001	<.001	3	4
PDAC	FOXK1 →	+0.336	+0.342	<.001	.001	3	4
LUAD	FOXK1_S223 →	+0.812	+0.544	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,943 associations by consensus.

CCZ1 vs POLR1E — BRCA

Explore this scatter interactively →