CCZ1

Across TCGA cell cohorts, CCZ1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,024 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible CCZ1-associated GO terms across cancer lineages are Meiotic mismatch repair, Positive regulation of isotype switching to IgG isotypes, and rRNA 2'-O-methylation. Each is linked with CCZ1 in more than 12 cancer types. Because this analysis shows association rather than direction, both CCZ1-to-partner and partner-to-CCZ1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Meiotic mismatch repair grouped by CCZ1-low versus CCZ1-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCZ1→partner) and Y-score (partner→CCZ1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Meiotic mismatch repair →	+0.107	+0.901	<.001	<.001	3	13
BLOOD_Myeloma	Positive regulation of isotype switching to IgG isotypes →	+0.144	+1.118	<.001	.002	3	12
SKIN	rRNA 2'-O-methylation →	+0.090	+0.610	<.001	<.001	3	9
BLOOD_Lymphoma	ER to Golgi ceramide transport →	+0.103	+0.691	<.001	<.001	3	9
BLOOD_Myeloma	Regulation of isotype switching to IgG isotypes →	+0.102	+1.250	.001	<.001	3	7
LIVER	Cellular response to nitrogen levels →	+0.151	+0.772	.002	.004	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,024 associations by consensus.

Meiotic mismatch repair by CCZ1 expression — SKIN

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