CCT7

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, CCT7 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated CCT7 data layer compared with 28 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher CCT7 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated CCT7 expression acts as an unfavorable survival marker, although some lineages such as HNSC and COAD show a favorable association.

LUAD, HNSC, and COAD are the cancer types where CCT7 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
LUADOSQuartileAll0.6100.926.00317view →
HNSCOSMedianAll1.0000.449.02310view →
COADDFSMedianIII,IV1.0000.844.0446view →
CCRCCOSTertileAll0.7200.884.0203view →
PDACDFSMedianAll0.4300.280.0332view →
LSCCDFSQuartileII,III,IV0.8350.440.0402view →
Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

CCT7–LUAD (OS)

Kaplan–Meier survival curve for CCT7 mass-spec protein-high vs -low samples in LUAD.

Open the LUAD breakdown →

Exploration