CCT7

Across TCGA pan-cancer cohorts, CCT7 RNA differs between tumor and matched normal tissue in 15 of 18 cancer types tested, making tumor–normal expression one of CCT7’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where CCT7 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CCT7 is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

COAD, HNSC, and BLCA are the cancer types where CCT7 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CCT7 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	II,III,IV	+1.385	<.001	12	view →
HNSC	Male	IV	+1.069	<.001	12	view →
BLCA	Female	All	+0.713	<.001	10	view →
KIRC	Female	All	+0.487	<.001	10	view →
LIHC	Female	II,III,IV	+1.166	<.001	9	view →
LUAD	Male	All	+0.717	<.001	9	view →
LUSC	Male	II,III,IV	+1.238	<.001	8	view →
READ	All	II,III,IV	+1.042	<.001	7	view →
STAD	Male	II,III,IV	+0.950	<.001	7	view →
BRCA	All	III,IV	+0.447	<.001	6	view →
KICH	Female	II,III,IV	−1.207	<.001	5	view →
UCEC	All	III,IV	+0.598	.002	4	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 15 lineages.

CCT7–COAD

Open the COAD breakdown →