Across TCGA pan-cancer cohorts, CCSER1 mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated CCSER1 data layer compared with 26 for mass-spec protein and 10 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher CCSER1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated CCSER1 expression acts as an unfavorable survival marker, although some lineages such as CCRCC show a favorable association.

LUAD and CCRCC are the cancer types where CCSER1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Median	II,III,IV	0.378	0.925	.022	16	view →
CCRCC	OS	Median	All	0.958	0.504	.010	9	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: CCSER1 tumor-vs-normal RNA expression · all CCSER1 data types