CCRL2

Across TCGA patient cohorts, CCRL2 mutation is significantly associated with the RNA expression of many other genes, with 2,341 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCRL2-associated genes across cancer lineages are IFNWP4, RNU6-1228P, and RN7SKP188. Each is linked with CCRL2 in more than 2 cancer types. Because this analysis shows association rather than direction, both CCRL2-to-partner and partner-to-CCRL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IFNWP4 grouped by CCRL2-low versus CCRL2-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCRL2→partner) and Y-score (partner→CCRL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	IFNWP4 →	+0.181	+6.221	<.001	.001	3	3
HNSC	RNU6-1228P →	+0.439	+6.468	<.001	.001	3	2
SKCM	RN7SKP188 →	+0.064	+3.743	<.001	.002	3	2
SKCM	DPY19L4P2 →	+0.042	+2.369	<.001	.008	3	2
UCEC	SMIM28 →	+0.279	+1.641	<.001	.004	3	2
SKCM	C17orf98 →	+0.188	+2.469	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,341 associations by consensus.

IFNWP4 by CCRL2 expression — HNSC

Explore this box plot interactively →