CCR6

Across TCGA patient cohorts, CCR6 protein abundance is significantly associated with the RNA expression of many other genes, with 9,971 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CCR6-associated genes across cancer lineages are TLR10, TRAJ35, and TRAJ30. Each is linked with CCR6 in more than 2 cancer types. Because this analysis shows association rather than direction, both CCR6-to-partner and partner-to-CCR6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCR6 versus TLR10 in BRCA, with a Pearson correlation of 0.70.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCR6→partner) and Y-score (partner→CCR6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TLR10 →	+2.091	+1.533	<.001	.009	3	3
BRCA	TRAJ35 →	+1.932	+1.515	<.001	<.001	3	3
BRCA	TRAJ30 →	+2.460	+1.573	<.001	.001	3	3
LUAD	SIRPB3P →	+0.429	+0.683	<.001	<.001	3	3
BRCA	IGKV7-3 →	+2.317	+1.590	.001	.006	3	2
BRCA	TRAJ10 →	+1.828	+1.135	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,971 associations by consensus.

CCR6 vs TLR10 — BRCA

Explore this scatter interactively →