CCR5

Across TCGA patient cohorts, CCR5 protein abundance is significantly associated with the RNA expression of many other genes, with 341 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible CCR5-associated genes across cancer lineages are RNU6-653P, RNU6-1147P, and RN7SL619P. Each is linked with CCR5 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCR5-to-partner and partner-to-CCR5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCR5 versus RNU6-653P in BRCA, with a Pearson correlation of 0.83.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCR5→partner) and Y-score (partner→CCR5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RNU6-653P →	+1.134	+1.462	<.001	.004	3	1
BRCA	RNU6-1147P →	+1.134	+1.462	<.001	.004	3	1
BRCA	RN7SL619P →	+1.310	+1.557	<.001	.005	3	1
LUAD	CYTH4 →	+0.437	+0.425	.003	.004	3	1
LUAD	LMF2 →	+0.280	+0.419	.008	.002	3	1
LUAD	IL2RB →	+0.609	+0.477	.008	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 341 associations by consensus.

CCR5 vs RNU6-653P — BRCA

Explore this scatter interactively →