Across TCGA patient cohorts, CCR3 mutation is significantly associated with the RNA expression of many other genes, with 1,775 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCR3-associated genes across cancer lineages are RN7SL392P, CYCSP49, and RPL31P47. Each is linked with CCR3 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCR3-to-partner and partner-to-CCR3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCR3→partner) and Y-score (partner→CCR3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RN7SL392P →	+0.032	+2.806	<.001	.009	3	2
COAD	CYCSP49 →	+0.100	+4.821	.003	.003	3	2
COAD	RPL31P47 →	+0.087	+4.225	<.001	.007	3	2
COAD	MIR8055 →	+0.759	+3.589	.001	.006	3	2
LIHC	MIR670 →	+0.350	+6.169	<.001	<.001	3	2
UCEC	SEC13 →	+0.479	+3.732	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,775 associations by consensus.

Exploration

CCR3 survival (RNA) · tumor vs normal (RNA) · all CCR3 data types