CCP110

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CCP110 mutation is significantly associated with the RNA expression of many other genes, with 3,386 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCP110-associated genes across cancer lineages are RN7SL248P, TUBBP11, and LINC01385. Each is linked with CCP110 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCP110-to-partner and partner-to-CCP110 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL248P grouped by CCP110-low versus CCP110-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCP110→partner) and Y-score (partner→CCP110) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRN7SL248P →+0.051+2.915<.001.00132
COADTUBBP11 →+0.284+5.087<.001.00232
COADLINC01385 →+0.172+3.660.001.00132
CESCLARP7P2 →+0.194+3.542.004.00732
UCECMIA-RAB4B →+0.057+1.682<.001.00132
SKCMLINC02639 →+0.181+2.528<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,386 associations by consensus.

RN7SL248P by CCP110 expression — UCEC

Box plot of RN7SL248P in CCP110-low vs CCP110-high samples in UCEC.

Explore this box plot interactively →

Exploration