CCNP

Across TCGA patient cohorts, CCNP mutation is significantly associated with the RNA expression of many other genes, with 115 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCNP-associated genes across cancer lineages are RN7SL148P, MIR4435-2, and OTOS. Each is linked with CCNP in more than 1 cancer types. Because this analysis shows association rather than direction, both CCNP-to-partner and partner-to-CCNP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL148P grouped by CCNP-low versus CCNP-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCNP→partner) and Y-score (partner→CCNP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RN7SL148P →	+0.222	+5.721	.009	.001	3	2
COAD	MIR4435-2 →	+0.412	+4.893	<.001	.005	3	2
SKCM	OTOS →	+0.277	+3.894	.002	.004	3	2
UCEC	RNA5SP113 →	+0.793	+4.003	<.001	.001	3	2
UCEC	RN7SL401P →	+0.107	+3.715	.004	.002	3	2
BLCA	ADAM24P →	+0.013	+4.685	.002	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 115 associations by consensus.

RN7SL148P by CCNP expression — COAD

Explore this box plot interactively →